Axitinib for research
Axitinib
CAS: 319460-85-0
Molecular Formula: C22H18N4OS
Axitinib for research - Names and Identifiers
| Name | Axitinib |
| Synonyms | AG013736 Axitinib AXITINIB AG 013736 AG-013736 AG 013736 AVERMECTINB Axitinib for research N-METHYL-2-{[3-((E)-2-PYRIDIN-2-YLVINYL)-1H-INDAZOL-6-YL]SULFANYL}BENZAMIDE N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide N-methyl-2-({3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl}sulfanyl)benzamide Benzamide, N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]- N-Methyl-2-((3-((1E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide |
| CAS | 319460-85-0 |
| InChI | InChI=1/C22H18N4OS/c1-23-22(27)18-7-2-3-8-21(18)28-16-10-11-17-19(25-26-20(17)14-16)12-9-15-6-4-5-13-24-15/h2-14H,1H3,(H,23,27)(H,25,26)/b12-9+ |
Axitinib for research - Physico-chemical Properties
| Molecular Formula | C22H18N4OS |
| Molar Mass | 386.47 |
| Density | 1.35g/cm3 |
| Boling Point | 668.9°C at 760 mmHg |
| Flash Point | 358.3°C |
| Solubility | Soluble in DMSO (42 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), ethanol (<1 mg/ml a |
| Vapor Presure | 9.35E-18mmHg at 25°C |
| Storage Condition | -20℃ |
| Refractive Index | 1.728 |
| MDL | MFCD09837898 |
| Use | An inhibitor of Flt and Flk (VEGFR) with antitumor properties |
Axitinib for research - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
| Safety Description | S60 - This material and its container must be disposed of as hazardous waste. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
| UN IDs | UN 3077 9 / PGIII |
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